Ronald L Neppl, Ph.D.   |  Principal Investigator

Ron received his B.S. and M.S. in Biomedical Engineering from Marquette University. He then worked in industry for a few years before returning to academia. He received his Ph.D. from the University of Virginia in Biophysics, where under the mentorship of Drs. Andrew and Avril Somlyo, he studied signal transduction in vascular smooth muscle. For his postdoctoral research, he then joined the laboratory of Dr. Da-Zhi Wang at Boston Children's Hospital where he focused on studying the roles of microRNAs and novel proteins that modulate the activity of the RNA Induced Silencing Complex in cardiac and skeletal muscle. He then moved to the laboratory of Dr. Kenneth Walsh and focused on long non-coding RNAs that modulate skeletal muscle growth processes before joining the faculty in the Department of Orthopedic Surgery at Brigham and Women's Hospital.


Eleonora Guagadnin, Ph.D.  |  Postdoctoral Fellow

Eleonora received her B.S. M.Sc. in Medical Biotechnologies from the University of Padova in Italy. She then interned in Dr. Marco Sandri’s lab at the Venetian Institute for Molecular Medicine in Padova, where she studied the role of mitochondrial remodeling in skeletal muscle atrophy. She then joined the laboratory of Dr. Yi-Wen Chen at the Children’s National Medical Center in Washington, D.C., where she studied the effects of TGFβ1 on skeletal muscle mass. She received her Ph.D. in Veterinary Sciences from the University of Padova under the mentorship of Dr. Carsten Bonnemann at the National Institutes of Health where she studied the transcriptional events responsible for onset and progression of Collagen type VI-related muscular dystrophy. Currently, she is focused on uncovering the roles of lncRNAs in the regulation of myogenesis and hypertrophic growth.


Benjamin Mason, B.S.  |  Technician

Ben is a recent graduate of Rensselaer Polytechnic Institute with a B.S. in Biomedical Engineering. While at RPI, he conducted research on the use of electrospun fibers as guidance scaffolds for neurite growth. In addition, he has experience in the application of protein engineering methodologies towards improving the specificity and efficacy of antibodies used in oncology therapeutics. In the future he hopes to pursue a P.h.D in Biomedical Engineering.

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Jun Li, M.D.  |  Ph.D. Candidate

Jun received his MD in First Affiliated Medical School of Wu Han University in China. He went through the resident standardization training of Orthopedics in Ren Min Hospital of Wuhan University. He then became a PhD canditate in West China School of medicine, Sichuan University, where he learned Orthopedics surgeries from professor Lei Liu and studied the restoration of bone defect using modified heterogeneous deproteinizated bone and bone marrow mesenchymal stem cells. Currently, he is currently focused on investigating the roles of long non-coding RNAs in the regulation of myogenesis and the treatment of volumetric muscle loss.